Jun 23

Chemical Profile and Clinical Efficacy of Micro-Fragmented Adipose-derived MSC Therapy in the Treatment of Knee Osteoarthritis

Check out the new article by long-time TOBI faculty, Dr. Gerard Malanga, published in Biologic Orthopedic Journal. By the year 2040, it is estimated that 25% of adults in the US will be diagnosed with osteoarthritis by a physician.  Osteoarthritis, considered as a progessive joint disorder due to “wear and tear,” has been described by researchers to involve a complex dynamic of pro-inflammatory mediators leading to an increase of enzymes that degrade soft-tissue supporting the joint. This article looks at...

Feb 9

January 2017: TOBI Faculty Publications in Regenerative Medicine

TOBI Faculty Publications: January 2017 January 2017, Stem Cells and Development Autologous and Allogeneic Equine Mesenchymal Stem Cells Exhibit Equivalent Immunomodulatory Properties In Vitro. TOBI Faculty C. Wayne McIlwraith, MD, published this study evaluating different methods of modulating inflammatory processes related to acute or chronic musculoskeletal injuries in the horse. They conducted studies to assess the immunological properties of equine allogeneic BMDMSCs compared with those of autologous BMDMSCs. For assessment of inherent immunogenicity, the relative ability of allogeneic and autologous...